Newly regulated carcinogen requires analysis – techniques for quantification of N-nitrosodimethylamine (NDMA)
New Zealand drinking water regulators have introduced new limits for N-nitrosodimethylamine, a carcinogenic compound often abbreviated to NDMA, in drinking water. These levels are very low (0.0001mg/L) and will require specific testing methods to determine if drinking water suppliers meet the new requirements. NDMA has been found in drinking water across the globe, and many analytical techniques have been used to identify and measure it. This review briefly summarises the health risks, formation and prevalence of NDMA in a drinking water context, before discussing the analytical techniques that are used to quantify NDMA at the required levels of sensitivity. The most common techniques are preconcentration by solid-phase extraction or solid-phase microextraction, followed by separation by gas or liquid chromatography and finally detection by mass spectrometry or chemiluminescence.